Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Biphosphonates in children: present and future].

I Kone Paut1, J M Gennari, K Retornaz

  • 1Service de pédiatrie, hôpital Nord, Chemin-des-Bourrelys, 13915 Marseille, France. ikonepau@ap-hm.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|September 11, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Serum angiotensin-converting enzyme has low diagnostic value for pediatric sarcoid uveitis.

Journal francais d'ophtalmologie·2024
Same author

[Immunosuppressive therapy in severe or chronic pediatric uveitis: Review of the literature].

Journal francais d'ophtalmologie·2021
Same author

Real-life study of the role of high-flow nasal cannula for bronchiolitis in children younger than 3 months hospitalised in general pediatric departments.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2020
Same author

Non accidental repeated lithium poisoning in a child: The role of hair analysis.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2020
Same author

[Therapeutic strategy for the treatment of non-infectious uveitis proposed by an expert panel].

La Revue de medecine interne·2018
Same author

Posterior elements disruption with hybrid constructs in AIS patients: is there an impact on proximal junctional kyphosis?

Archives of orthopaedic and trauma surgery·2017
Same journal

Family experiences of paediatric palliative care during hospital-at-home: a systematic review.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Knowledge of maternity caregivers on vaccination BCG recommendations and circuits.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

"CRANIOQUALITY study: Quality of life in children with non-syndromic craniosynostosis after surgery".

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Chronological evolution of brain imaging of hemiconvulsion-hemiplegia-epilepsy from 5 cases in Mayotte island.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Point-of-care capillary blood ketone testing to predict the need for intravenous or nasogastric tube rehydration in children with acute gastroenteritis.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Transition practices of patients with inflammatory bowel disease from pediatric to adult healthcare systems. Results from a national survey.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
See all related articles

Bisphosphonates, used for Paget disease, inhibit bone resorption and are effective in pediatric osteoporosis, hypercalcemia, and heterotopic calcifications. Further multicentric studies are needed to establish pediatric efficacy and guidelines.

Area of Science:

  • Pharmacology
  • Biochemistry
  • Pediatrics

Context:

  • Bisphosphonates are synthetic pyrophosphate analogs.
  • Primary use is Paget disease of bone.
  • Mechanism involves osteoclastic activity inhibition.

Purpose:

  • To review the use of bisphosphonates in pediatric disorders.
  • To highlight their efficacy in specific conditions.
  • To discuss the potential for expanded use in children.

Summary:

  • Bisphosphonates are effective in treating childhood osteoporosis, particularly osteogenesis imperfecta, hypercalcemia, and heterotopic calcifications.
  • Despite successful use, there's a lack of controlled studies and long-term follow-up.
  • Newer, oral, potent bisphosphonates with minimal effects on bone mineralization may expand pediatric applications.

Related Experiment Videos

Impact:

  • Bisphosphonates offer therapeutic options for pediatric bone disorders.
  • Further research is crucial for optimizing their use in children.
  • Development of guidelines for pediatric bisphosphonate therapy is needed.