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[Inhaled corticosteroids in asthma in infants and young children]
C Thumerelle1, C Santos, D Penel-Capelle
1Unité de pneumologie pédiatrique, hôpital Jeanne de Flandre, CHRU de Lille, 59037 Lille, France.
Insights
Inhaled corticosteroids are a primary asthma treatment for children and adults. New data support their use in toddlers and preschoolers, detailing efficacy, side effects, and prescription guidelines.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
Context:
- Asthma management in young children presents unique challenges due to disease heterogeneity.
- Inhaled corticosteroids (ICS) are standard for older children and adults.
Purpose:
- To review evidence supporting ICS use in toddlers and preschool children.
- To outline efficacy, safety, and prescribing practices for ICS in early childhood asthma.
Summary:
- Controlled trials demonstrate the efficacy of inhaled corticosteroids in young asthmatic patients.
- Potential side effects and current indications for ICS therapy are discussed.
- Guidelines for the appropriate prescription of ICS in pediatric asthma are provided.
Impact:
- Informs clinical practice regarding ICS use in early childhood asthma.
- Provides evidence-based recommendations for managing asthma in toddlers and preschoolers.
- Aims to optimize treatment outcomes and minimize risks associated with ICS therapy.
Abstract:
Inhaled corticosteroids have become the mainstain in the treatment of asthmatic children and adults. Asthma in infancy and early childhood is a heterogeneous condition, with different disease phenotypes and outcome. However, rationale data justifying the use of inhaled corticosteroids in toddlers and preschool children are now available. We recall the results of controlled trials studying the efficacy of inhaled corticosteroids, their potential side-effects, and their actual indications and modalities of prescription.