[Asthma in infants and young children. Prevention, challenge of the 21st century?]

P Le Roux1, F Toutain, B Le Luyer

  • 1Département de pédiatrie, groupe hospitalier, 55 bis, rue Gustave-Flaubert, 76600 Le Havre, France. pleroux@ch-havre.fr

Insights

Preventing infant asthma involves prenatal factors like maternal diet and smoke exposure. Prolonged breastfeeding and avoiding environmental allergens are key protective strategies for high-risk infants.

Area of Science:

  • Pediatrics
  • Allergology
  • Public Health

Background:

  • Asthma prevention in infants and children is a significant public health concern.
  • Primary prevention strategies target prenatal and early life exposures.
  • The impact of infections and lifestyle on asthma risk remains debated.

Purpose of the Study:

  • To review current strategies for the primary prevention of infant and childhood asthma.
  • To highlight key factors influencing asthma development from conception through the first year of life.

Main Methods:

  • Literature review of studies on infant and childhood asthma prevention.
  • Analysis of factors including maternal exposures, breastfeeding, infections, lifestyle, and environmental measures.

Main Results:

  • Prenatal factors (maternal smoke, diet, allergen exposure) are crucial for primary prevention.
  • Prolonged breastfeeding demonstrates a protective effect against allergy and asthma development.
  • Environmental interventions like smoke avoidance and allergen reduction are recommended for high-risk infants.

Conclusions:

  • Early life interventions, including prenatal care and breastfeeding, are vital for asthma prevention.
  • Environmental control measures are essential for infants at high risk of developing asthma.
  • Further research is needed to clarify the role of infections and lifestyle in asthma etiology.

Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...