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[Effect of po li gan capsule on immunofunction in mice]
1Department of Pharmacology, School of Basic Medical Sciences, WCUMS, Chengdu 610041.
Abstract:
This study aimed at the immune response of mice to Po Li Gan Capsule (PLGC). The effects of PLGC on phagocytosis of phagocyte, on serum hemolysin, and on IL-1, IL-2 in mice were investigated. The results showed that the coefficient and index of phagocytosis obviously increased in the experiment group, compared with that in the control group (P < 0.01); the serum hemolysin in the experiment group increased too (P < 0.01). The results also showed that PLGC could restore the capacity of macrophage for secreting IL-1 that had been inhibited by cyclophosphamide and PLGC could enhance the release of IL-2 from spleen cell in the experiment group (P < 0.05-0.01). These suggest that PLGC enhances both cellular and humoral immunity function in mice.