Related Experiment Video
Updated: Aug 19, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
Published on: December 27, 2010
[A molecular epidemiologic study of TT virus in various population]
1Liver Disease Research Center, Second Affiliated Hospital, Hunan Medical University, Changsha 410011.
Abstract:
To investigate infection and sequence divergence of TT virus in various population, a nested polymerase chain reaction (nPCR) assay with primers from TTV ORF1 genome was used to detect serum TTV DNA. TTV DNAs from various population were cloned and sequenced. Six gene sequences derived from two patients with non-A through non-E and non-G hepatitis, a hepatitis patient with HBsAg, a normal blood donor, an intravenous drug user and a woman prostitute, were compared with known sequence of TTV isolate (N22) reported by Okamoto, Japan. The nucleotide homology were 96%-98% and the whole sequences belonged to la genotype. The data indicate that TTV DNA from various population in China might chiefly be la genotype. There is no correlation between genotype and disease transmission and development.
Related Concept Videos
Single Nucleotide Polymorphisms-SNPs
Modern Molecular Taxonomy
Applications of Molecular Taxonomy
Toxoplasmosis

