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[Atypical mesoblastic nephroma: histopathological entity or specific anatomoclinical form?]
Maha Driss1, Karima Mrad, Jean-Christophe Sabourin
1Service d'anatomie et cytologie pathologiques, Institut Salah-Azaiez, 1006 Bab Saadoun, Tunis, Tunisie.
Bulletin Du Cancer
|September 6, 2002
Summary
Atypical mesoblastic nephroma, a rare infant kidney tumor, shows a good prognosis when diagnosed before 3 months and surgically removed. Two infants with this condition recovered well after complete tumor resection.
Area of Science:
- Pediatric Oncology
- Nephropathology
Background:
- Atypical mesoblastic nephroma (AMN) is a rare renal neoplasm predominantly affecting infants.
- Early diagnosis and complete surgical resection are crucial for favorable outcomes.
Observation:
- This report details two cases of AMN in infants aged 2 and 3 months.
- Tumors exhibited dense cellularity, high mitotic activity, cystic degeneration, and necrosis.
Findings:
- Both tumors were completely excised with clear surgical margins.
- Patients remain disease-free 9 and 14 months post-surgery, indicating a positive prognosis.
Implications:
- These cases support the favorable prognosis of AMN in infants under 3 months with complete surgical removal.
- Highlights the importance of prompt diagnosis and aggressive surgical management for pediatric renal tumors.