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Published on: October 12, 2017
Immature ureteric jet doppler patterns and urinary tract infection and vesicoureteric reflux in children
Vivian Yee Fong Leung1, Con Metreweli, Chung Kwong Yeung
1Diagnostic Radiology and Organ Imaging Department, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China. leuyf2@ctimail.com
Insights
The monophasic ureteric jet pattern, an indicator of immaturity, is frequently observed in children with urinary tract infections (UTI) and vesicoureteric reflux (VUR). Its persistence is strongly linked to these conditions.
Area of Science:
- Pediatric Nephrology
- Diagnostic Ultrasound
- Urology
Background:
- The Doppler waveform of the ureteric jet reflects ureteric peristalsis modified by the vesicoureteric junction (VUJ) sphincteric mechanism.
- A monophasic pattern in ureteric jets is considered indicative of physiological immaturity.
Purpose of the Study:
- To investigate the correlation between the immature monophasic ureteric jet pattern and the presence of urinary tract infection (UTI) and vesicoureteric reflux (VUR) in pediatric patients.
Main Methods:
- Doppler ultrasound assessment of ureteric jets was performed.
- The study included 241 healthy children and 98 children diagnosed with UTI.
- The prevalence of the monophasic pattern was analyzed in relation to age, UTI, and VUR status.
Main Results:
- The monophasic pattern was observed in 29% of healthy children, with significant age-related variation (nearly universal in infants <6 months, <15% in older children).
- This immature pattern was significantly more prevalent in children with UTI (73.5%) and VUR (90.5%) compared to healthy controls (p = 0.0005).
Conclusions:
- The persistence of the monophasic ureteric jet pattern in children is strongly associated with an increased likelihood of urinary tract infection (UTI) and vesicoureteric reflux (VUR).
- This finding suggests the monophasic pattern may serve as a valuable, albeit immature, indicator in the diagnostic workup of pediatric urinary issues.
Abstract:
The Doppler waveform of the ureteric jet is the result of modification of ureteric peristalsis by an active sphincteric mechanism of the vesicoureteric junction (VUJ). The monophasic pattern is associated with immaturity. This study set out to see the correlation between this immature pattern with urinary tract infection (UTI) and vesicoureteric reflux (VUR) in children. Ureteric jets of 241 healthy children and 98 children with UTI were studied. The monophasic pattern was found in 29% of healthy children overall, but varied greatly according to age. The monophasic pattern was virtually universal in the first 6 months of life, dropping to below 15% in late childhood. This immature pattern was more commonly seen in the UTI (73.5%) and VUR (90.5%) groups than in the healthy controls. The difference was statistically significant (p = 0.0005 for both). The persistence of this immature pattern was highly associated with UTI and VUR.
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