Immature ureteric jet doppler patterns and urinary tract infection and vesicoureteric reflux in children

Vivian Yee Fong Leung1, Con Metreweli, Chung Kwong Yeung

  • 1Diagnostic Radiology and Organ Imaging Department, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China. leuyf2@ctimail.com

Insights

The monophasic ureteric jet pattern, an indicator of immaturity, is frequently observed in children with urinary tract infections (UTI) and vesicoureteric reflux (VUR). Its persistence is strongly linked to these conditions.

Area of Science:

  • Pediatric Nephrology
  • Diagnostic Ultrasound
  • Urology

Background:

  • The Doppler waveform of the ureteric jet reflects ureteric peristalsis modified by the vesicoureteric junction (VUJ) sphincteric mechanism.
  • A monophasic pattern in ureteric jets is considered indicative of physiological immaturity.

Purpose of the Study:

  • To investigate the correlation between the immature monophasic ureteric jet pattern and the presence of urinary tract infection (UTI) and vesicoureteric reflux (VUR) in pediatric patients.

Main Methods:

  • Doppler ultrasound assessment of ureteric jets was performed.
  • The study included 241 healthy children and 98 children diagnosed with UTI.
  • The prevalence of the monophasic pattern was analyzed in relation to age, UTI, and VUR status.

Main Results:

  • The monophasic pattern was observed in 29% of healthy children, with significant age-related variation (nearly universal in infants <6 months, <15% in older children).
  • This immature pattern was significantly more prevalent in children with UTI (73.5%) and VUR (90.5%) compared to healthy controls (p = 0.0005).

Conclusions:

  • The persistence of the monophasic ureteric jet pattern in children is strongly associated with an increased likelihood of urinary tract infection (UTI) and vesicoureteric reflux (VUR).
  • This finding suggests the monophasic pattern may serve as a valuable, albeit immature, indicator in the diagnostic workup of pediatric urinary issues.

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