Polypharmacy, age, and scheduled surgery
Related Experiment Videos
1Department of Anesthesiology, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, USA.
Study Objective:
To test the hypothesis that there is a correlation between the age of patients who present for scheduled surgery and the number of drugs taken by these patients.
Design:
Prospective clinical study.
Setting:
Outpatient admissions.
Patients:
150 ASA physical status I, II, and III patients 40 years of age or older, scheduled for outpatient surgery.
Interventions:
None.
Measurements:
Age, medical history, and prescription and nonprescription medications of these patients were recorded.
Main Results:
There was no significant difference among number of drugs taken by patients in different age groups [40 to 49 years: 3.2 +/- 3.1 (average number of drugs taken, standard deviation); 50 to 59 years: 3.6 +/- 3.1; 60 to 69 years: 4.0 +/- 2.9; 70 to 79 years: 4.4 +/- 2.7; 80+ years: 3.7 +/- 2.2].
Conclusions:
Medical condition, which may, in part, be a function of biological age and not chronological age, is the primary determinant of the number of medications taken by patients presenting to an outpatient clinic for scheduled surgery.
Related Concept Videos
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacodynamics in Geriatric Patients: Effects of Age
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion