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Related Experiment Videos

Microbial cellulose utilization: fundamentals and biotechnology.

Lee R Lynd1, Paul J Weimer, Willem H van Zyl

  • 1Chemical and Biochemical Engineering, Thayer School of Engineering and Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA. lee.lynd@dartmouth.edu

Microbiology and Molecular Biology Reviews : MMBR
|September 5, 2002
PubMed
Summary

This study explores microbial cellulose utilization, detailing enzyme systems, microbial physiology, and ecological factors. It also examines consolidated bioprocessing strategies for efficient biomass conversion.

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Area of Science:

  • Biochemistry
  • Microbiology
  • Biotechnology

Background:

  • Microbial cellulose utilization is key for biomass conversion.
  • Understanding cellulase enzyme systems and microbial physiology is crucial.

Purpose of the Study:

  • To comprehensively examine microbial cellulose utilization across multiple levels of biological organization.
  • To explore strategies for consolidated bioprocessing (CBP) of cellulosic biomass.

Main Methods:

  • Review of fundamental features of microbial cellulose utilization.
  • Analysis of methodological approaches for studying cellulose degradation.
  • Examination of organism development strategies for CBP.

Main Results:

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  • Detailed examination of biomass structure, microbial diversity, enzyme systems, and ecological factors.
  • Quantitative descriptions of cellulose hydrolysis, including enzyme adsorption and kinetics.
  • Evaluation of two distinct strategies for consolidated bioprocessing.

    • Conclusions:

    • Identified unresolved issues in microbial cellulose utilization.
    • Proposed approaches to resolve these issues.
    • Contrasted microbially-oriented vs. enzymatically-oriented cellulose hydrolysis paradigms.