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Demonstration of acute ischemic lesions in the fetal brain by diffusion magnetic resonance imaging

Cristina Baldoli1, Andrea Righini, Cecilia Parazzini

  • 1Neuroradiology Department, Università Salute e Vita IRCCS-San Raffaele, Milan, Italy.

Annals of Neurology
|September 5, 2002
PubMed

The possibility of detecting acute hypoxic-ischemic brain lesions by prenatal magnetic resonance imaging or ultrasound is low. We present a case of a fetus with a vein of Galen arteriovenous malformation in whom prenatal diffusion-weighted magnetic resonance imaging at 33 weeks of gestation clearly detected cerebral acute ischemic lesions, associated with remarkable decrease of the average apparent diffusion coefficient, whereas T2-weighted imaging was still not informative.

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...