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Related Experiment Videos

Adult-onset tic disorders.

Valsamma Eapen1, Andrew J Lees, J P W F Lakke

  • 1Department of Psychiatry and Behavioural Sciences, Royal Free and University College, London Medical School, London, United Kingdom.

Movement Disorders : Official Journal of the Movement Disorder Society
|September 5, 2002
PubMed
Summary

Adult-onset motor tics and vocalizations present differently than childhood-onset Gilles de la Tourette syndrome. These adult cases show more severe symptoms, social issues, and less response to medication.

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Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Adult-onset tic disorders are less understood than childhood-onset variants.
  • Gilles de la Tourette syndrome (GTS) is typically diagnosed in childhood.

Observation:

  • This study observed 8 patients with adult-onset motor tics and vocalizations.
  • Three patients reported childhood compulsive tendencies.
  • Three patients had a family history of tics or obsessive-compulsive behavior.

Findings:

  • Adult-onset tic disorders are associated with more severe symptoms compared to younger-onset GTS.
  • These patients experienced greater social morbidity and potential trigger events.
  • Increased sensitivity and poorer response to neuroleptic medication were noted.

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Implications:

  • Understanding adult-onset tics is crucial for accurate diagnosis and treatment.
  • These findings suggest distinct pathophysiological mechanisms for adult-onset tic disorders.
  • Further research is needed to develop targeted therapies for adult tic disorders.