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Thromboembolic disease and cancer: possible new treatments
Allan D Angerio1, Dorothy A Fink
1Department of Physiology and Biophysics, School of Nursing and Health Studies, Georgetown University, Washington, DC, USA.
Critical Care Nursing Quarterly
|September 5, 2002
Abstract:
Hypoxia-induced endothelin (ET) and vascular endothelial growth or permeability factor (VEGF) play an important role in tumor biology by promoting angiogenesis. Angiogenesis alters hemostasis and promotes thromboembolic disease (TED). Therapeutic angiogenesis directed against ET and VEGF may reduce the incidence of TED in cancer patients.