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Primary extranodal malignant lymphoma affecting the periodontium
Brian L Mealey1, George S Tunder, Charles W Pemble
1Department of Periodontics, Wilford Hall Medical Center, Lackland Air Force Base, TX 78236-5346, USA.
Journal of Periodontology
|September 5, 2002
Summary
Primary extranodal non-Hodgkin's lymphoma rarely affects the gingiva. Early diagnosis and complete excision are crucial for successful treatment and patient survival.
Area of Science:
- Oral oncology
- Head and neck cancer
- Hematologic malignancies
Background:
- Non-Hodgkin's lymphoma (NHL) can manifest in extranodal head and neck tissues, with rare occurrences in the gingiva.
- Prompt diagnosis and treatment of extranodal NHL are critical for patient outcomes.
Observation:
- A case of primary extranodal large B-cell lymphoma presenting as a small gingival lesion is described.
- The lesion was initially presumed benign and treated with simple excision.
Findings:
- Microscopic examination revealed primary extranodal large B-cell lymphoma, necessitating further treatment.
- The patient received chemotherapy and radiation therapy, remaining disease-free for 3 years post-treatment.
Implications:
- This case underscores the necessity of submitting all excised tissues for histopathological evaluation, regardless of apparent benignity.
- Complete surgical excision with wide margins is vital for managing suspected lesions.
- Periodontal plastic surgery techniques can effectively manage post-biopsy defects, ensuring favorable esthetic results.