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[Effect of propofol and propofol combined with ketamine on cardiovascular system]
1Department of Anensthesiology, Second Affiliated Hospital, Hunan Medical University, Changsha 410011.
Objective:
To prevent blood pressure from reducing caused by injection of propofol.
Methods:
Thirty patients, ASA Grade I-II, were randomly allocated into one of the two groups: Group I (Group P, n = 15) and Group II (Group K + P, n = 15), the patients received 2 mg.kg-1 propofol in Group I and 1 mg.kg-1 ketamine before equal dose of propofol in Group II. Systolic blood pressure(SBP), diastolic blood pressure(DBP), mean blood pressure and heart rate were measured before injection and 1 min, 3 min, 5 min and 10 min respectively after injection.
Results:
Blood pressure in Group I was significantly lower than Group II.
Conclusion:
Ketamine can attenuate the hemodynamic responses to propofol.