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Published on: March 22, 2012
[Detection of D -dimer in pleural effusion]
1Department of Internal Medicine, Second Affiliated Hospital, Hunan Medical University, Changsha 410011.
Abstract:
The content of D -dimer in pleural fluid of different causes was examined by the ELISA method in 45 patients. The results were that the contents of D -dimer in both tuberculous and empyema pleural effusions were significantly higher than in malignant pleural effusion (P < 0.01; P < 0.05). D -dimer was positively correlated with lactic dehydrogenase (LDH) in pleural fluid (r = 0.4168, P < 0.01). The results suggest that fibrinolytic activities in tuberculous and empyema pleural effusion are much higher than in malignant pleural effusion. The detection of D -dimer in pleural fluid may reflect the extent of pleural inflammation and be helpful in the differential diagnosis of pleural effusion.
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