[Expression of heat shock protein (HSP70) in normal endometrium and endometrial carcinomas]

Expression of heat shock protein 70 (HSP70) in normal endometrium tissue and endometrial carcinoma was analyzed by the present authors to determine the relationship between HSP70 expression and the prognosis of endometrial carcinomas. The immunohistochemical reactivity of monoclonal antibodies against HSP70 was examined in 44 endometrial carcinomas and 40 normal endometria HSP70 respectively. HSP70 was expressed stronger in carcinomas than in normal. Expression of HSP70 was found in 56.82% of endometrial carcinomas and was well correlated with histological grade (P < 0.05). These results suggest that HSP70 may play a role in the prognosis of endometrial carcinomas.