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[A case of Pseudomans aeruginosa pneumonia complicated with multiple pustular skin lesions]
Yoshiko Miyajima1, Syunji Mizunoe, Ryoutarou Morinaga
1Department of Respiratory Medicine, Oita National Hospital.
Abstract:
Pseudomonas aeruginosa is a common causative agent of septicemia in compromised host and the entry site of organism is most commonly the respiratory and genitourinary tract. P. aeruginosa septicemia is often associated with vesicular or pustular skin lesions, subcutaneous nodules, deep abscess, cellulites and bullae. We report a case of P. aeruginosa pneumonia with multiple pustular skin lesions on the chest and leg. A 77-year-old male was admitted to our hospital complaining of fever, productive cough and eruptions. Laboratory findings revealed a leucocytosis (14,830/microliter) and an elevated CRP (21.72 mg/dl). The chest radiograph and computed tomography revealed a fluid level in preexisting bullae and a consolidation shadow with multiple cavities in the right upper lobe and nodular shadow with cavity in the left lower lobe. P. aeruginosa strain was isolated from the bronchial lavage and pustule. Blood cultures were negative. Skin biopsy specimens showed histologically a dense infiltrate of neutrophils in the horny cell layer. He was diagnosed as Pseudomonas aeruginosa pneumonia complicated with multiple pustular skin lesions. He was treated with antimicrobial agents for 24 days and his clinical condition improved.
Insights
This case study highlights Pseudomonas aeruginosa pneumonia in an immunocompromised patient, presenting with severe pustular skin lesions. Prompt diagnosis and antimicrobial treatment led to clinical improvement.
Area of Science:
- Infectious Diseases
- Pulmonology
- Dermatology
Background:
- Pseudomonas aeruginosa is a significant pathogen in compromised hosts, frequently entering through the respiratory or genitourinary tract.
- P. aeruginosa septicemia can manifest with various skin lesions, including pustules, nodules, and abscesses.
Observation:
- A 77-year-old male presented with fever, cough, and widespread pustular eruptions.
- Imaging revealed Pseudomonas aeruginosa pneumonia with cavities and fluid in bullae.
- The pathogen was isolated from bronchial lavage and skin pustules; blood cultures were negative.
Findings:
- The patient was diagnosed with Pseudomonas aeruginosa pneumonia complicated by multiple pustular skin lesions.
- Histopathology of skin biopsy confirmed a dense neutrophil infiltrate.
Implications:
- This case underscores the importance of considering P. aeruginosa in pneumonia with unusual skin manifestations.
- Early identification and targeted antimicrobial therapy are crucial for managing severe P. aeruginosa infections.
- Further research into the pathogenesis of P. aeruginosa-associated skin lesions is warranted.
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