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Published on: January 4, 2018
Causes of insulin resistance in childhood
Alison Jeffery1, Linda Voss, Brad Metcalf
1Early Bird Research Centre, Derriford Hospital, Plymouth. alison.jeffery@phnt.swest.nhs.uk
Insights
Rising type 2 diabetes cases are a global concern. High body weight is a key factor, alongside genetics and environment, influencing healthcare provider worries.
Area of Science:
- Endocrinology
- Public Health
- Metabolic Diseases
Background:
- Global rise in type 2 diabetes mellitus (T2DM) incidence.
- T2DM etiology involves complex genetic and environmental interactions.
- Obesity is increasingly recognized as a primary contributor to T2DM.
Observation:
- Healthcare practitioners express significant concern regarding T2DM prevalence.
- Literature review identifies multiple predisposing factors for T2DM.
- High body weight emerges as a particularly convincing factor.
Findings:
- Review synthesizes current literature on T2DM predisposing factors.
- Identifies key elements contributing to healthcare provider apprehension.
- Highlights the significant role of obesity in T2DM development.
Implications:
- Informs public health strategies for T2DM prevention and management.
- Guides clinical practice and patient education on weight management.
- Underscores the need for further research into T2DM etiology and risk factors.
Abstract:
The increasing incidence of type 2 diabetes worldwide is causing concern. Genetic and environmental influences have been put forward to explain the origins of this disease, but perhaps the most convincing contributory factor is high body weight. The authors review the literature on the subject to identify some of the predisposing factors influencing healthcare practitioners' concerns about the issue.
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