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A relocated technique of atomic force microscopy (AFM) samples and its application in molecular biology
Aiguo Wu1, Zhuang Li, Lihua Yu
1Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Jilin.
Ultramicroscopy
|September 6, 2002
Abstract:
A kind of simple atomic force microscopy (AFM) relocated technique, which takes advantage of homemade sample locator system, is used for investigating repeatedly imaging of some specific species on the whole substrate (over 1 x 1 cm2) with resolution about 400 nm. As applications of this sample locator system, single extended DNA molecules and plasmid DNA network are shown in different AFM operational modes: tapping mode and contact mode with different tips after the substrates have been moved.