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30 mm regeneration of rat sciatic nerve along collagen filaments
Satoru Yoshii1, Masanori Oka, Mitsuhiro Shima
1Institute of Biomedical Engineering, Kansai Denryoku Hospital, Imaichi 2-7-14, Asahi-ku, 535-0011 Osaka, Japan. K-20433@kepco.co.jp
Brain Research
|September 6, 2002
Abstract:
This paper describes 30 mm regeneration of peripheral nerve axons along collagen filaments; 31-mm-long collagen filaments or collagen tube were grafted to bridge a 30-mm defect of rat sciatic nerve. The mean number and the diameter of regenerated myelinated axons were 330+/-227 and 2.7+/-0.9 microm at the distal end of the collagen-filaments 12 weeks postoperatively; while at the distal end of the tube no axon was found.