Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transcription attenuation.

Paul Gollnick1, Paul Babitzke

  • 1Department of Biological Sciences, State University of New York, Buffalo, NY 14260, USA. gollnick@acsu.buffalo.edu

Biochimica Et Biophysica Acta
|September 6, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canonical transcription termination mechanisms explain a minority of operons in cyanobacteria.

mSystems·2026
Same author

EXPRESSION OF CONJUGATION GENES IS CONTROLLED BY PROCESSIVE ANTITERMINATION AND A NOVEL ZIPPER-TYPE TRANSCRIPTIONAL ATTENUATION MECHANISM.

bioRxiv : the preprint server for biology·2025
Same author

Canonical transcription termination mechanisms explain a minority of operons in cyanobacteria.

bioRxiv : the preprint server for biology·2025
Same author

Characterization of bacterial intrinsic transcription terminators identified with TERMITe - a novel method for comprehensive analysis of Term-seq data.

bioRxiv : the preprint server for biology·2025
Same author

Characterization of bacterial intrinsic transcription terminators identified with TERMITe-a novel method for comprehensive analysis of Term-seq data.

Nucleic acids research·2025
Same author

Applying the brakes to transcription: regulation of gene expression by RNA polymerase pausing.

Journal of bacteriology·2025
Same journal

Cumulative Contents.

Biochimica et biophysica acta·2020
Same journal

Molecular Basis of Disease Cumulative Contents.

Biochimica et biophysica acta·2020
Same journal

General Subjects Cumulative Contents.

Biochimica et biophysica acta·2020
Same journal

Erratum to 'on the role of exchangeable hydrogen bonds for the kinetics of P680<sup>+·</sup> Q<sub>A</sub> <sup>-·</sup> formation and P680<sup>+·</sup> Pheo<sup>-·</sup> recombination in photosystem II' [Biochim. Biophys. Acta 1276 (1996) 35-44].

Biochimica et biophysica acta·2019
Same journal

Oligomeric state of the light-harvesting complexes B800-850 and B875 from purple bacterium Rubrivivax gelatinosus in detergent solution.

Biochimica et biophysica acta·2019
Same journal

Regulation of pigment content and enzyme activity in the cyanobacterium Nostoc sp. Mac grown in continuous light, a light-dark photoperiod, or darkness.

Biochimica et biophysica acta·2019
See all related articles

Bacteria control gene expression using transcription attenuation and antitermination. These processes involve RNA structures regulated by ribosomes, RNA-binding proteins, transfer RNA, and antisense RNA to adapt to environmental changes.

Area of Science:

  • Microbiology
  • Molecular Biology
  • Gene Regulation

Background:

  • Bacteria precisely regulate gene expression to adapt to environmental fluctuations.
  • Transcription elongation control is a key regulatory mechanism.
  • Attenuation and antitermination are major strategies for modulating gene expression.

Purpose of the Study:

  • To review mechanisms bacteria employ for transcription elongation control.
  • To explore how attenuation and antitermination regulate gene expression.
  • To examine the biomolecules involved in influencing RNA structure during these processes.

Main Methods:

  • Review of existing literature on bacterial transcription regulation.
  • Analysis of biomolecular interactions affecting RNA structure.

Related Experiment Videos

  • Categorization of regulatory mechanisms based on involved molecules.

    • Main Results:

    • Attenuation is often controlled by ribosomes translating leader peptides, especially in enteric bacteria.
    • RNA-binding proteins regulate attenuation in Gram-positive bacteria like Bacillus subtilis.
    • Transfer RNA and antisense RNA play roles in antitermination and attenuation, respectively, in various bacterial systems.

    Conclusions:

    • Diverse biomolecules, including ribosomes, RNA-binding proteins, tRNA, and antisense RNA, are crucial for bacterial transcription regulation.
    • Attenuation and antitermination are versatile mechanisms enabling bacteria to respond to environmental cues.
    • Understanding these regulatory pathways is vital for comprehending bacterial adaptation and gene expression control.