[Changes in monoamine fluorescence in the hypothalamus of rats under the influence of hydrocortisone]

The histochemical fluorescent method was applied to the study of the effect of hormones of the adrenal cortex on the catecholamine content in the rat hypothalamus. Administration of hydrocortisone proved to decrease the amount of monoamines in the adrenergic fibers located in the periventricular area and the lateral portion of the midhypothalamus, this being expressed in a reduced intensity of their fluorescence in these formations. The mentioned changes were apparently associated with a specific effect of the hormone and could be related to the regulation of the corticosteroid level by the "reverse connection" mechanism.