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Adverse dermatologic effects of cardiovascular drug therapy: part II
William H Frishman1, Brian D Brosnan, Marc Grossman
1Departments of Medicine and Dermatology, New York Medical College, Valhalla, New York 10605, USA.
Insights
Cardiovascular drugs, including antiarrhythmics, ACE inhibitors, ARBs, and diuretics, can cause various skin reactions. This review details these adverse dermatologic responses to aid physicians in patient care.
Area of Science:
- Cardiology
- Dermatology
- Pharmacology
Background:
- Cardiovascular disease (CVD) prevalence increases with aging populations.
- Pharmacologic therapies are crucial for managing CVD and improving patient quality of life.
- Adverse drug reactions, particularly dermatologic responses, are potential complications of CVD medications.
Purpose of the Study:
- To review and categorize cutaneous reaction patterns associated with cardiovascular drug use.
- To provide clinicians with information on adverse dermatologic effects of specific cardiovascular drug classes.
Main Methods:
- Literature review of adverse dermatologic responses to cardiovascular medications.
- Focus on antiarrhythmic agents (Class III, IV, and others), ACE inhibitors, Angiotensin II receptor blockers (ARBs), and diuretics.
Main Results:
- Cardiovascular drugs can manifest a wide spectrum of adverse dermatologic reactions.
- Specific reaction patterns are linked to different classes of cardiovascular medications.
Conclusions:
- Awareness of potential cutaneous side effects is essential for physicians prescribing cardiovascular drugs.
- Understanding these dermatologic reactions can improve patient management and treatment adherence.
Abstract:
Cardiovascular disease is common, affecting an increasing number of persons as the population ages. To combat this growing health problem, physicians use a multitude of medications in the treatment of their patients. Although pharmacologic therapy greatly enhances quality of life for a majority of patients, there is always the potential for an unfavorable reaction. For example, cardiovascular drugs can induce a vast array of adverse dermatologic responses. This article reviews the various cutaneous reaction patterns that can occur as a result of treatment with class III, IV, and other antiarrhythmic agents, ACE inhibitors, Angiotensin II receptor blockers, and diuretics.