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Related Experiment Videos

Pre-counseling education materials for BRCA testing: does tailoring make a difference?

Celette Sugg Skinner1, Joellen M Schildkraut, Donald Berry

  • 1Duke University Medical Center, Department of Community and Family Medicine and the Duke Comprehensive Cancer Center, Durham, NC 27710, USA. celette.skinner@duke.edu

Genetic Testing
|September 7, 2002
PubMed
Summary
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Tailored print materials (TPMs) significantly improved knowledge and risk perception for genetic testing among women at high risk for breast and ovarian cancer. TPMs were more effective than non-tailored materials in aiding informed decision-making.

Area of Science:

  • Medical Genetics
  • Health Communication
  • Decision Science

Background:

  • Effectiveness of tailored print materials (TPMs) for behavioral targets is known, but their role as decision aids for genetic testing was unevaluated.
  • Women with personal/family histories of breast/ovarian cancer and a high probability (>10%) of BRCA1/BRCA2 mutations are candidates for genetic testing.

Purpose of the Study:

  • To compare the effectiveness of TPMs versus non-tailored print materials (NPMs) in improving knowledge and risk perception for genetic testing.
  • To assess the impact of TPMs on informed decision-making for BRCA1/BRCA2 genetic testing.

Main Methods:

  • A randomized controlled trial involving 325 women at high risk for hereditary breast and ovarian cancer.
  • Participants received either TPMs or NPMs with similar content on genetic testing.

Related Experiment Videos

  • Follow-up surveys assessed knowledge, risk perception, and reactions to the materials.

    • Main Results:

    • TPM recipients showed a significantly greater increase in correct knowledge responses (24% vs. 16%) compared to NPM recipients.
    • TPM recipients had significantly less over-estimation of their risk for carrying a mutation (40% vs. 70%).
    • TPMs were perceived as more personalized and informative, though anxiety levels did not differ between groups.

    Conclusions:

    • TPMs are effective decision aids for genetic testing, significantly enhancing knowledge and accurate risk perception.
    • These improvements are critical components for facilitating informed decision-making regarding genetic testing for hereditary cancer syndromes.
    • Personalized print materials offer a valuable tool in genetic counseling and risk communication.