Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New directions in neuronal migration.

Mary E Hatten1

  • 1Laboratory of Developmental Neurobiology, The Rockefeller University, 1230 York Avenue, New York, NY 10021-6399, USA. hatten@rockefeller.edu

Science (New York, N.Y.)
|September 7, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term maintenance of H3K27me3 in postmitotic neurons is dispensable for gene expression regulation.

bioRxiv : the preprint server for biology·2026
Same author

ASTN2 in ASD and neurodevelopmental disorders.

Current topics in developmental biology·2026
Same author

G-quadruplexes as a source of vulnerability in BRCA2<i>-</i>deficient granule cell progenitors and medulloblastoma.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Conference Report: Cerebellar Development and Disease at Single-Cell Resolution.

Cerebellum (London, England)·2025
Same author

Histone bivalency in CNS development.

Genes & development·2025
Same author

Mice lacking <i>Astn2</i> have ASD-like behaviors and altered cerebellar circuit properties.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026
Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026
Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026
Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026
Same journal

Retraction.

Science (New York, N.Y.)·2026
Same journal

Making time.

Science (New York, N.Y.)·2026
See all related articles

Genetic analyses reveal conserved molecular mechanisms guiding neuronal migration in both invertebrates and vertebrates. These findings enhance our understanding of central nervous system development and evolution.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Genetics

Background:

  • Neuronal migration is crucial for central nervous system (CNS) development.
  • Understanding the molecular basis of neuronal migration is key to deciphering developmental processes.
  • Genetic approaches have recently provided significant insights into these mechanisms.

Purpose of the Study:

  • To review the molecular mechanisms of neuronal migration.
  • To highlight the conservation of these mechanisms across species.
  • To discuss the integration of different migratory pathways in CNS development.

Main Methods:

  • Review of recent genetic analyses and molecular studies.
  • Comparative analysis of migratory mechanisms in invertebrates and vertebrates.

Related Experiment Videos

  • Discussion of genetic approaches defining molecular pathways.

    • Main Results:

    • Many molecular mechanisms guiding invertebrate neuronal migration are conserved in vertebrates.
    • These conserved mechanisms control various migration patterns, including radial, tangential, and anterior-posterior movements.
    • Genetic studies have elucidated the specific molecules and pathways involved.

    Conclusions:

    • Neuronal migration involves a complex interplay of conserved molecular mechanisms.
    • Understanding these mechanisms provides insights into CNS development and evolution.
    • Genetic analysis is a powerful tool for dissecting neuronal migration pathways.