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[Levodopa dependency in Parkinson's disease: case report and review]
U Müller1, M Reuter, W Hermann
1Klinik und Poliklinik für Psychiatrie, Universität Leipzig, Germany. muelleru@cns.mpg.de
Der Nervenarzt
|September 7, 2002
Abstract:
Only a few patients with Parkinson's disease and levodopa dependency or abuse have been reported. We present a 35-year-old patient with young-onset Parkinson's disease who developed motor complications, levodopa dependency, and drug-induced psychosis after primary treatment with levodopa. Diagnostic criteria and treatment guidelines for this neuropsychiatric disorder are presented as well as a tentative neurobiological answer to the question of why levodopa dependency is observed only in a minority of patients with Parkinson's disease.