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Updated: Jan 31, 2026
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A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
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Pulmonary autograft mitral valve replacement: initial experience with the Ross II procedure
S Roy1, A Mohanty, A Sampath Kumar
1Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi.
Indian Heart Journal
|September 10, 2002
Summary
The Ross II procedure, using a pulmonary autograft for mitral valve replacement in calcific mitral valve disease, shows promising results in selected patients. Survivors experienced excellent autograft function post-procedure.
Area of Science:
- Cardiovascular Surgery
- Cardiac Valve Replacement
- Thoracic Surgery
Background:
- Growing interest in pulmonary autograft for mitral valve replacement.
- Focus on selected patient populations for this procedure.
Purpose of the Study:
- Evaluate the feasibility and outcomes of the Ross II procedure for mitral valve replacement.
- Assess the efficacy of pulmonary autografts in patients with calcific mitral valve disease.
Main Methods:
- Performed the Ross II procedure on 10 patients (30-52 years) with calcific mitral valve disease.
- Utilized pulmonary autografts for mitral valve replacement.
- Confirmed diagnosis and autograft function with transthoracic and transesophageal echocardiography.
Main Results:
- 8 of 10 patients survived the early post-operative period.
- Survivors improved to New York Heart Association functional class I.
- Excellent autograft and homograft function observed at a mean follow-up of 9 months.
Conclusions:
- The Ross II procedure is a viable option for mitral valve replacement in specific patients with calcific mitral valve disease.
- The procedure is technically challenging and necessitates a valve bank.
- Positive functional outcomes and graft performance support its consideration.
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