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Published on: May 15, 2020
Outcome of venous stasis ulceration when complicated by arterial occlusive disease
W T Bohannon1, R B McLafferty, S T Chaney
1Division Vascular Surgery, Department of Surgery, Southern Illinois University, School of Medicine, Springfield, Illinois 62794, USA.
Insights
Patients with venous stasis ulceration (VSU) and severe arterial occlusive disease (AOD) have a rare, serious condition. Healing is uncommon, and mortality is high, even after arterial procedures.
Area of Science:
- Vascular surgery
- Wound healing
- Geriatric medicine
Background:
- Venous stasis ulceration (VSU) and severe arterial occlusive disease (AOD) are distinct vascular conditions.
- The combined presence of VSU and AOD presents a complex clinical challenge, particularly in elderly patients.
Purpose of the Study:
- To investigate the outcomes of patients diagnosed with both VSU and severe AOD.
- To evaluate the effectiveness of interventions aimed at improving arterial inflow in this patient population.
Main Methods:
- A retrospective study design was employed.
- Patient data were identified using ICD-9 codes for VSU and AOD from 1989 to 1999 across two tertiary hospitals.
- Inclusion criteria required the presence of VSU and an ipsilateral procedure for AOD or major amputation during the same hospitalization.
Main Results:
- Fourteen patients (15 extremities) with a mean age of 80 years were identified.
- The mean duration of VSU was 6.4 years, with a mean wound area of 71 cm² and ankle-brachial index of 0.46.
- Interventions included bypass (60%), interventional procedures (20%), sympathectomy (0.6%), and amputation (13%). Over a mean follow-up of 2.8 years, only 23% of extremities healed, with high mortality.
Conclusions:
- The combination of VSU and AOD is rare, primarily affecting elderly individuals with comorbidities.
- Complete healing of venous stasis ulcers is infrequent despite arterial revascularization procedures.
- High short-term mortality rates were observed in this patient cohort.
Objective:
to report the outcome of patients with venous stasis ulceration (VSU) and severe arterial occlusive disease (AOD).
Design:
retrospective study.
Methods:
using the International Classification of Diseases (ICD-9), codes for VSU and AOD were cross-matched to identify patients from 1989 to 1999 at two tertiary hospitals. Entry into the study required the presence of a VSU and an ipsilateral procedure to improve AOD or major amputation during the same hospitalisation.
Results:
fourteen patients (15 extremities) with a mean age of 80 years (range: 47-93) were identified as having VSU and AOD. Mean duration of VSU up to the time of revascularisation or amputation was 6.4 years (range: 4 months-21 years). The mean number of VSUs per extremity was 2.1 and mean wound area was 71 cm(2). Mean ankle-brachial index was 0.46 (range: 0.10-0.78). Nine extremities (60%) had a bypass procedure, 3 (20%) had an interventional procedure, 1 (0.6%) had a lumbar sympathectomy, and 2 (13%) had an amputation. Over a mean follow-up of 2.8 years, 3 extremities (23%) healed of which 2 recurred. On last review, 11 patients with 12 afflicted extremities had expired. Nine of the remaining 10 extremities were not healed at the time of death. Eight of nine bypass grafts remained patent in follow-up or at death and subsequent limb salvage was 100%.
Conclusions:
combined VSU and AOD represents a rare condition predominantly found in elderly patients with multiple comorbidities. Few patients had complete healing despite an arterial inflow procedure and mortality was high over the short term.
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