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UniBLAST: a system to filter, cluster, and display BLAST results and assign unique gene annotation
Yan Zhou1, Guyang Matthew Huang, Liping Wei
1Institute of Genetics, State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, 220 Handan Road, Shanghai 200433, People's Republic of China.
Motivation:
More and more often, a gene is epitomized by a large number of sequences in GenBank. This high redundancy makes it very difficult to identify a unique best match for a query sequence from its BLAST results. We developed a novel program UniBLAST that filters out uninformative hits, clusters the redundant hits, groups the hits by LocusLink, and graphically displays the results. We also implemented a scoring function in UniBLAST to assign a unique gene name to a query sequence. UniBLAST significantly increases the efficiency of gene annotation.
Availability:
The program is available at http://south.genomics.org.cn/software/uniblast/index.html
Contact:
uniblast@genomics.org.cn; wei@nexusgenomics.com