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PeCoP: automatic determination of persistently conserved positions in protein families
Iddo Friedberg1, Hanah Margalit
1Department of Molecular Genetics and Biotechnology, The Hebrew University--Hadassah Medical School, 91120, Jerusalem, Israel. idoerg@burnham.org
Bioinformatics (Oxford, England)
|September 10, 2002
Abstract
Unlabelled:
PeCoP is a WWW-based service which accepts a protein sequence, and reports positions that are conserved in close and distant sequence family members. The collation of family members is performed using iterative PSI-BLAST runs. Examining positional conservation in close and distant family members enables a better selection of positions that may play a role in determining the protein's structure and function.
Availability:
http://bioinformatics.org/pecop
Contact:
idoerg@burnham.org
Supplementary Information:
http://bioinformatics.org/pecop/about_pecop