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[Acute complications in cocaine users].

Emmanuel Guerot1, Olivier Sanchez, Jean-Luc Diehl

  • 1Service de Réanimation Médicale, Hôpital Européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris Cedex 15, France. emmanuel.guerot@hop.egp.ap-hop-paris.fr

Annales De Medecine Interne
|September 10, 2002
PubMed
Summary

Cocaine use leads to serious health issues, primarily cardiovascular events like chest pain and myocardial ischemia. Prompt diagnosis via urine tests and symptomatic treatment, including benzodiazepines, are crucial for managing these cocaine intoxication complications.

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Area of Science:

  • Cardiology
  • Toxicology
  • Emergency Medicine

Context:

  • Cocaine use has risen significantly over the past two decades.
  • Clinical presentations of cocaine intoxication are diverse, with a strong emphasis on cardiovascular complications.

Purpose:

  • To outline the varied clinical manifestations and complications associated with cocaine use.
  • To emphasize the importance of ruling out myocardial ischemia in patients presenting with chest pain due to cocaine intoxication.

Summary:

  • Cardiovascular events are predominant, including chest pain, myocardial ischemia, left ventricular dysfunction, arrhythmia, endocarditis, and aortic dissection.
  • Non-cardiac complications span neurological (seizures, stroke), respiratory (pulmonary issues), renal (kidney failure), and obstetrical disorders.

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  • Diagnosis is confirmed by urine cocaine detection, with treatment focusing on symptom management and benzodiazepine administration.
  • Impact:

    • Highlights the critical need for awareness among healthcare providers regarding the spectrum of cocaine-induced pathologies.
    • Informs clinical practice for the timely diagnosis and management of acute cocaine toxicity.
    • Underscores the significant public health burden associated with the increasing prevalence of cocaine abuse.