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Updated: Aug 14, 2026

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
[Rectal endocrine intermediate-cell carcinoma]
Dominique Béchade1, Jérôme Desramé, Olivier Berthelet
1Service de Clinique Médicale, Hospital du Val-de-Grace, Paris, Cedex, France. bechade.dominique@wanadoo.fr
Abstract:
An 82-year-old patient complained of diarrhea due to a rectal endocrine intermediate-cell carcinoma. Histology displayed a neuron-specific enolase and CD56 immunoreactive tumor. Hepatic metastases developed rapidly and the tumor was briefly reactive to radiotherapy and chemotherapy. These tumors are rare and have a poor prognosis. We focus on the recent classification of gastrointestinal endocrine tumors.

