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Central precocious puberty in girls with Williams syndrome
Carl-Joachim Partsch1, Insa Japing, Reiner Siebert
1University Hospital Kiel, Christian-Albrechts-Universität zu Kiel, Germany.
The Journal of Pediatrics
|September 10, 2002
Abstract:
We report an estimated prevalence of precocious puberty of 1 in 5 to 6 girls with Williams syndrome (18.3%). Mean menarcheal age of 86 girls with Williams syndrome was 11.5 +/- 1.7 (+/-SD) years. Distribution of menarcheal age was significantly different from that in normal girls (12.9 +/- 1.1 years; n = 759).