Effects of the N-salicylaladehyde Aminoglucose Schiff Base Complexes no O(2)(-). and DNA
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Updated: Sep 29, 2026

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
Published on: May 29, 2019
Xiao-Qin Liu1, Jian-Lin Wang, Zhi-Feng Le
1Hubei Sanxia College Medical College, Yichang 443003, China.
Abstract:
The effects of SG schiff base complexes with Cu(II), Zn(II), Co(III) on O(2)(-). and DNA were studied. The results showed that both CuSG and ZnSG could an inhibit the synthesis of O(2)(-). markedly. The inhibiting effect of CuSG was larger than that of ZnSG. Complexes CuSG and CoSG could also combine with the salmon sperm DNA. The intrinsic association constant (K(0)) for CuSG and CoSG were estimated to be 2.86x10(4) M(-1 and 1.29x105) M-1 respectively. The numbers of binding sites per 100 nucleotide (n) were 2.5 and 7.5 respectively.
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