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Nutritional rickets in young Nigerian children in the Sahel savanna
G O Akpede1, E A Solomon, I Jalo
1University of Maiduguri, Nigeria.
Insights
Biochemical rickets is prevalent in young children, particularly males and older children. Dietary calcium deficiency, alongside vitamin D deficiency, is a key factor in nutritional rickets within the Sahel savanna region.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Nutritional rickets is a significant health concern in under-five populations.
- Understanding the prevalence and contributing factors is crucial for effective intervention.
Purpose of the Study:
- To determine the prevalence of clinical and biochemical rickets in out-patients under five years old.
- To correlate biochemical rickets with family sociocultural characteristics.
- To assess the response of nutritional rickets to vitamin D therapy.
Main Methods:
- Prospective cross-sectional and retrospective case-series surveys were conducted.
- Data collection involved clinical examinations, maternal interviews, and biochemical assessments.
- Nutritional rickets management utilized stoss therapy.
Main Results:
- Prevalence of clinical and biochemical rickets was 4%, with 17% having biochemical rickets only.
- Biochemical rickets prevalence was higher in males and increased with age.
- Lower prevalence was observed in indigenous families, Moslem families, and children of less educated mothers or those in specific occupations.
Conclusions:
- The study supports the hypothesis that dietary calcium deficiency is as important as vitamin D deficiency in nutritional rickets etiology in the Sahel savanna.
- Sociocultural factors significantly influence the prevalence of biochemical rickets.
Objectives:
To determine the prevalence of clinical and biochemical rickets in an under-five out-patient population, relate the prevalence of biochemical rickets (BR) to the sociocultural characteristics of families and determine the response of nutritional rickets to vitamin D therapy.
Design:
Prospective cross-sectional and retrospective case-series surveys.
Setting:
Paediatric general out-patient and consultant clinics.
Subjects:
One hundred and ninety eight out-patients and twenty two patients aged >1 to 60 months treated for nutritional rickets.
Interventions:
Clinical examination, interview with mothers and determination of biochemical abnormalities of under-fives and management of patients with rickets using stosstherapy.
Main Outcome Measures:
Prevalence of BR and response to stosstherapy.
Results:
Eight (4%) patients in the survey had clinical and biochemical rickets while 33 (17%) had biochemical rickets only; 92 (47%) other patients had isolated hypocalcaemia and/or hypophosphataemia. The prevalence of BR was higher in males (p <0.05), and increased with age (p <0.001). The prevalence was lower in families who were indigenous to the area (p <0.05), children of Moslem families (p <0.05) and children whose mothers were full-time housewives, unskilled or traders (p <0.01), and who lacked any formal western education (p = 0.157). Three of the seven evaluable patients who received stosstherapy responded late.
Conclusion:
The results support the hypothesis that deficiency or reduced availability of dietary calcium may be of at least equal importance with vitamin D deficiency in the aetiology of nutritional rickets in the Sahel savanna.
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