Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulsatile ocular blood flow during pregnancy.

M Centofanti1, R Migliardi, S Bonini

  • 1Ophthalmology Clinic, Tor Vergata University, Roma, Fondazione G.B. Bietti per l'Oftalmologia Onlus, Italy.

European Journal of Ophthalmology
|September 11, 2002
PubMed
Summary

Pulsatile ocular blood flow (POBF) significantly increases during pregnancy, with higher levels observed in the second trimester compared to the first. These changes may be influenced by hormonal shifts during gestation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of MUC1 proteolytic cleavage sites in vivo.

Biochemical and biophysical research communications·2001
Same author

Intractable insomnia after cessation of treatment with thalidomide.

Gastroenterology·2001
Same author

Eradication of Helicobacter pylori for non-ulcer dyspepsia.

The Cochrane database of systematic reviews·2001
Same author

[Beyond "successful aging: Rembrandt in his self-portraits].

Psychiatrische Praxis·2001
Same author

Sonographic diagnosis of a pneumothorax inapparent on plain radiography: confirmation by computed tomography.

The Journal of trauma·2001
Same author

Economics, competition and the regulation of public health risks.

Australian and New Zealand journal of public health·2001

Area of Science:

  • Ophthalmology
  • Physiology
  • Reproductive Medicine

Background:

  • Pregnancy involves significant physiological changes, including hormonal shifts that can affect various bodily systems.
  • Ocular blood flow is crucial for maintaining eye health, and its regulation may be altered during gestation.

Purpose of the Study:

  • To investigate changes in pulsatile ocular blood flow (POBF) throughout pregnancy.
  • To compare POBF in pregnant women with non-pregnant controls.

Main Methods:

  • Twenty-seven healthy pregnant women were enrolled, with some followed from the first to the second trimester.
  • POBF, intraocular pressure (IOP), blood pressure (BP), and heart rate (HR) were measured using a pneumotonometer.
  • Statistical analysis included unpaired and paired Student t-tests.

Related Experiment Videos

Main Results:

  • POBF significantly increased from the first to the second trimester of pregnancy (p < 0.0008).
  • POBF in pregnant women was substantially higher than in non-pregnant controls (p = 0.00008).
  • No significant differences were observed in IOP, BP, or HR between groups or across trimesters.

Conclusions:

  • Pulsatile ocular blood flow (POBF) demonstrates a significant increase throughout gestation.
  • Elevated estrogen levels during pregnancy may contribute to increased POBF via endothelial-dependent vasodilation.
  • These findings suggest a dynamic adaptation of ocular hemodynamics during pregnancy.