Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nucleic acid testing for emerging viral infections.

J-P Allain1, I Thomas, S Sauleda

  • 1Division of Transfusion Medicine, Department of Haematology, East Anglia Blood Centre, Cambridge, UK. jpa1000@cam.ac.uk

Transfusion Medicine (Oxford, England)
|September 11, 2002
PubMed
Summary

New viruses like GBV-C/HGV and circoviruses (TTV, SEN-V) require transfusion safety assessments. Parvovirus B19 screening in plasma pools is crucial due to transmission risks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

Physical review letters·2024
Same author

[Multiplex nucleic acid testing: development and applications].

Virologie (Montrouge, France)·2023
Same author

Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment.

Physical review letters·2022
Same author

Pitfalls in the diagnosis of death using neurological criteria.

BJA education·2021
Same author

Current status of organ donation after brain death in the UK.

Anaesthesia·2020
Same author

Vaccinating wild animals against rabies.

Revue scientifique et technique (International Office of Epizootics)·2020

Area of Science:

  • Virology
  • Transfusion Medicine
  • Public Health

Background:

  • Technological advancements facilitate the discovery of novel viruses.
  • Assessing new infectious agents for transfusion relevance is critical.

Purpose of the Study:

  • To evaluate the transfusion safety implications of newly identified viruses.
  • To review the characteristics and screening strategies for transfusion-transmissible viruses.

Main Methods:

  • Literature review of viral identification and characterization.
  • Analysis of viral transmissibility, pathogenicity, and prevalence in blood donors.
  • Assessment of screening assay availability and nucleic acid testing (NAT) for viral detection.

Main Results:

Related Experiment Videos

  • GB virus-C/hepatitis G virus (GBV-C/HGV) is not linked to post-transfusion hepatitis but may affect HIV replication.
  • Human circoviruses (TTV, SEN-V) are ubiquitous and persistent; SEN-V may cause non-A-E hepatitis.
  • Parvovirus B19 transmission via plasma derivatives necessitates NAT screening of plasma pools.

Conclusions:

  • Vigilance in identifying and assessing new viruses is essential for blood safety.
  • Specific viruses like GBV-C/HGV, TTV, SEN-V, and Parvovirus B19 present distinct transfusion safety challenges.
  • Nucleic acid testing is vital for controlling parvovirus B19 transmission in plasma products.