Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sonicated transdermal drug transport.

Amit Joshi1, Jaideep Raje

  • 1Department of Chemical Technology, University of Mumbai, Matunga, Mumbai 400 019, India. joshiamtig@yahoo.com

Journal of Controlled Release : Official Journal of the Controlled Release Society
|September 11, 2002
PubMed
Summary

Sonicated transdermal drug transport (TDT) offers a promising alternative to conventional drug delivery. This method effectively overcomes the skin barrier, enhancing drug penetration for potential future applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic Reclassification and Survival Outcomes in Intermediate-Risk and Poor-Risk Nonseminomatous Germ Cell Tumors: Single-Institution Experience From Western India.

JCO global oncology·2026
Same author

Unveiling the variations in penile cancer care: identifying knowledge gaps and research priorities.

BMJ oncology·2026
Same author

Bladder Adjuvant Radiotherapy: Phase III Multicenter Randomized Controlled Trial of Adjuvant Radiotherapy or Observation for Postcystectomy Muscle-Invasive Bladder Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Prognostic Factors in Oropharyngeal Cancer Treated With Definitive Chemoradiotherapy.

Cancer medicine·2026
Same author

Pattern of resistance on first-line EGFR-directed therapy in EGFR-positive metastatic NSCLC.

Ecancermedicalscience·2026
Same author

Contemporary management of adrenocortical carcinoma: A narrative review.

Urologic oncology·2026

Area of Science:

  • Pharmacology
  • Biomedical Engineering
  • Materials Science

Background:

  • Transdermal drug transport (TDT) presents advantages over traditional administration routes.
  • The skin's stratum corneum (SC) acts as a significant barrier to drug permeation.
  • Current TDT methods are underutilized due to this barrier challenge.

Purpose of the Study:

  • To explore sonicated transdermal drug transport as a novel drug delivery system.
  • To detail the advantages of TDT and reasons for its limited use.
  • To explain how sonicated TDT overcomes the stratum corneum barrier.

Main Methods:

  • Review of sonophoresis principles and experimental setups.
  • Analysis of sonophoretic mechanisms, including cavitation, thermal effects, and mechanical stresses.

Related Experiment Videos

  • Discussion of drug-specific variations in sonophoretic enhancement and mathematical modeling.

    • Main Results:

    • Sonicated TDT effectively breaches the stratum corneum barrier.
    • Cavitation, thermal effects, convective transport, and mechanical stresses contribute to enhanced drug transport.
    • Sonophoretic enhancement varies significantly between different drugs.

    Conclusions:

    • Sonicated transdermal drug transport is a viable method for enhanced drug delivery.
    • Understanding sonophoresis mechanisms is crucial for optimizing drug transport.
    • Future applications of sonicated TDT are anticipated across various therapeutic areas.