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Updated: Aug 12, 2026

12:11
Determination of Fatty Acid Oxidation and Lipogenesis in Mouse Primary Hepatocytes
Published on: August 27, 2015
[Substrates and products of fatty acid elongation in mouse brain microsomes]
Biochimie
|January 1, 1975
Abstract:
In brain microsomes, palmitate and stearate elongation involve a membrane lipid-bound substrate. After elongation by malonyl-CoA, acyl-products are partially bound to proteins. Acyl-proteins are not found when endogenous fatty acid elongation takes place. In the dysmyelinating Quaking mouse mutants, "stearyl-membrane" substrate formation is normal; thus, the deficiency observed in very long chain fatty acid formation is not due to a lack in substrate formation.
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