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Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Bipolar disorder in adolescence and young adulthood
Peter M Lewinsohn1, John R Seeley, Maureen E Buckley
1Oregon Research Institute, 1715 Franklin Boulevard, Eugene, OR 97403-1983, USA. pete@ori.org
Abstract:
The purpose of this article is to present findings from the Oregon Adolescent Depression Project regarding full-syndrome and subthreshold bipolar disorder (BD) in adolescence and young adulthood. BD first incidence peaked around age 14 years. Adolescent BD showed significant continuity across developmental periods and was associated with adverse outcomes during young adulthood. Subthreshold BD results provide partial support for a bipolar spectrum.
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