[Blood serum and liver phospholipids in rats with chronic choline-protein deficiency]

Serum and liver phospholipids were studied in rats at different stages of pathological processes induced by a diet with a high fat content, but deficient in protein and choline. Such cirrhosogenic diet caused fatty infiltration, fibrosis and nodular liver cirrhosis in rats, depending on the period of its administration. This diet resulted in a considerable decrease of the phospholipid content in the liver and the serum of experimental rats. Addition of choline to the cirrhosogenic diet prevented formation of fatty infilitration in rats, but failed to protect completely from a fall of phospholipids in the liver.