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Left ventricular pressure responses in post-angiographic angina
Catheterization and Cardiovascular Diagnosis
|January 1, 1975
Summary
Patients with coronary heart disease experiencing angina after left ventricular cineangiography show increased left ventricular end-diastolic pressure. This suggests myocardial ischemia, prompting medical attention for elevated pressures post-procedure.
Area of Science:
- Cardiology
- Cardiovascular Physiology
Background:
- Coronary heart disease (CHD) patients may experience angina pectoris.
- Left ventricular cineangiography is an invasive diagnostic procedure.
- Understanding hemodynamic changes during and after cineangiography is crucial for patient management.
Purpose of the Study:
- To compare hemodynamic alterations in patients with post-angiographic angina versus spontaneous angina and asymptomatic controls.
- To identify pressure changes indicative of myocardial ischemia during left ventricular cineangiography.
Main Methods:
- Hemodynamic monitoring of left ventricular end-diastolic pressure and dp/dt in patients undergoing left ventricular cineangiography.
- Comparison between three groups: post-angiographic angina, spontaneous angina, and asymptomatic controls.
Main Results:
- Patients with post-angiographic angina exhibited a significantly greater increase in left ventricular end-diastolic pressure compared to other groups.
- No significant change in dp/dt was observed in patients with post-angiographic angina.
- A rise in end-diastolic pressure exceeding 20 mmHg post-cineangiography was associated with myocardial ischemia.
Conclusions:
- Post-angiographic angina is linked to increased left ventricular end-diastolic pressure, likely due to contrast-induced preload and anginal ventricular dysfunction.
- Elevated end-diastolic pressure post-left ventricular cineangiography serves as a critical alert for potential myocardial ischemia.