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Prognostic implications of admission inflammatory profile in acute ischemic neurological events
T Anuk1, E B Assayag, R Rotstein
1Department of Neurology and the Stroke Unit, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Objective:
To reveal the potential prognostic implications of admission inflammatory markers in patients with acute ischemic neurological events.
Patients And Methods:
Sixty patients with an acute ischemic neurological event who were examined within 24 h from the appearance of symptomatology. We determined the high-sensitive C-reactive protein (hs-CRP) concentrations, erythrocyte sedimentation rate (ESR), fibrinogen concentrations and degree of erythrocyte adhesiveness/aggregation.
Results:
A significant correlation was noted between baseline hs-CRP concentrations, ESR as well as adhesiveness/aggregation and the outcome of the ischemic neurological event as determined by the modified Rankin scale 8-12 months following the insult.
Conclusion:
Admission inflammatory markers have long-term prognostic implications in patients with acute ischemic neurological events. These findings are relevant in view of the new therapeutic interventions now available for reducing the inflammatory response.