Related Experiment Videos
A rapid PCR method of genotyping LDL receptor mutations in WHHL rabbits
Huijun Sun1, Shin-ichi Usui, Masashi Shiomi
1Department of Pathology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan.
Journal of Atherosclerosis and Thrombosis
|September 13, 2002
Abstract:
WHHL rabbits are a valuable model for the study of human familial hypercholesterolemia and atherosclerosis. To use this animal model, it is often necessary to confirm LDL receptor status in WHHL rabbits. Here, we described a simple and rapid PCR method to detect LDL mutations in WHHL rabbits.