Assessing the encoding of stimulus attributes with rapid sequences of stimulus events

In a preceding paper (M. Eger and R. Eckhorn, J. Comput. Neurosci., 2002) we have published a three step method for the quantification of transinformation in multi-input and -output neuronal systems. Here we present an extension that applies to rapid series of transient stimuli and thus, fills the gap between the discrete and continuous stimulation paradigm. While the three step method potentially captures all stimulus aspects, the present approach quantifies the discriminability of selected attributes of discrete stimuli and thus, assesses their encoding. Based on simulated and recorded data we investigate the performance of the implemented algorithm. Our approach is illustrated by analyses of neuronal population activity from the visual cortex of the cat, evoked by electrical stimuli of the retina.