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Published on: January 3, 2012
Additional case of Ramichloridium mackenziei cerebral phaeohyphomycosis from the Middle East
Z U Khan1, S J Lamdhade, M Johny
1Department of Microbiology, Faculty of Medicine, Kuwait University, Safat. ziauddin@hsc.k-univ.edu.kw
Abstract:
In this report we describe a case of cerebral phaeohyphomycosis involving a 56-year-old Egyptian male who worked as a mason in Kuwait for 6 years. Computerized tomography scan of the brain revealed presence of a large abscess in the left occipital lobe. Aspirated pus from the abscess showed branched, septate, hyphae with light brown pigmentation. Cultured pus grew the fungus Ramichloridium mackenziei. Despite amphotericin B (1 mg kg(-1) per day) therapy for 2 weeks, the patient expired. The isolate was later found to be resistant to amphotericin B ( > 32 microg ml(-1)). Antifungal susceptibility testing to other agents was also performed.
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