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Intravesical treatment of severe bacillus Calmette-Guerin cystitis
J Palou1, L Rodríguez-Villamil, A Andreu-Crespo
1Department of Urology and Pharmacy, Fundació Puigvert, Universitat Autònoma de Barcelona, Spain. urologia@fundacio-puigvert.es
Objective:
Intravesical instillation of bacillus Calmette-Guerin (BCG) is an established treatment of carcinoma in situ and recurrent superficial bladder tumours. The inflammatory reaction due to BCG provokes cystitis of short duration as a frequent side effect. When the symptomatology is severe and long-lasting, different systemic treatments have been administered with varying degrees of efficacy.
Material And Methods:
We have studied the treatment of severe BCG cystitis with a anaesthetic anti-inflammatory solution administered by intravesical instillations to 16 patients.
Results:
Good results were obtained in 94% of the cases, with immediate clinical improvement in terms of pain and urinary symptoms, and with no side effects.
Conclusions:
This treatment is inexpensive and easy to administer. We consider that it offers a useful option to solve an infrequent but very annoying problem for the patients.