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High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled
Stephen Derdak1, Sangeeta Mehta, Thomas E Stewart
1Pulmonary/Critical Care Medicine, Wilford Hall Medical Center, San Antonio, Texas 78236, USA. sderdak@mac.com
American Journal of Respiratory and Critical Care Medicine
|September 17, 2002
Abstract:
Observational studies of high-frequency oscillatory ventilation in adults with the acute respiratory distress syndrome have demonstrated improvements in oxygenation. We designed a multicenter, randomized, controlled trial comparing the safety and effectiveness of high-frequency oscillatory ventilation with conventional ventilation in adults with acute respiratory distress syndrome; 148 adults with acute respiratory distress syndrome (Pa(O2)/fraction of inspired oxygen