Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alternate cryogens for cryosurgery.

D Torre

    The Journal of Dermatologic Surgery
    |June 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Dermatologic cryosurgery needs a storable cryogen. Freons, like Freon 22, show promise as alternatives to liquid nitrogen for most office procedures, though their full toxicity is unknown.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Concepts in health professions education: Using the lens of concept mapping for further understanding. A new feature for Medical Teacher.

    Medical teacher·2023
    Same author

    AMEE 2009 spotlight on educational research.

    Medical teacher·2010
    Same author

    Insulin receptor and IGF1R are not required for oocyte growth, differentiation, and maturation in mice.

    Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation·2009
    Same author

    Impact of highly active antiretroviral therapy on organ-specific manifestations of HIV-1 infection.

    HIV medicine·2005
    Same author

    A review of HIV-1 Tat protein biological effects.

    Cell biochemistry and function·2004
    Same author

    A review of cardiovascular complications accompanying AIDS.

    Cell biochemistry and function·2004
    Same journal

    Dermabrasion for adenoma sebaceum.

    The Journal of dermatologic surgery·1976
    Same journal

    Squamous-cell carcinoma of the penis.

    The Journal of dermatologic surgery·1976
    Same journal

    Microtopography of the skin and scar formation.

    The Journal of dermatologic surgery·1976
    Same journal

    Reflections on skin surgery.

    The Journal of dermatologic surgery·1976
    Same journal

    Cosmetic surgery of the neck as an office procedure.

    The Journal of dermatologic surgery·1976
    Same journal

    M-plasty techniques.

    The Journal of dermatologic surgery·1976
    See all related articles

    Area of Science:

    • Dermatology
    • Cryosurgery
    • Medical Engineering

    Background:

    • Liquid nitrogen is the standard cryogen for dermatologic cryosurgery but is non-storable.
    • Existing alternatives like argon gas and nitrous oxide have limitations in feasibility or usefulness.

    Purpose of the Study:

    • To evaluate storable cryogens as alternatives to liquid nitrogen for dermatologic cryosurgery.
    • To identify practical cryogen options for office-based dermatological practices.

    Main Methods:

    • Testing of various freons (fluorinated hydrocarbons), including Freons 12, 22, and 13, alone or in mixtures.
    • Assessment of their suitability for dermatologic cryosurgery compared to liquid nitrogen.

    Main Results:

    Related Experiment Videos

  • Freons are capable of treating most lesions commonly addressed by cryosurgery in an office setting.
  • Freon 22 emerged as the most practical option for general dermatologic cryosurgery.
  • Freons do not achieve the extreme cold or penetration depth of liquid nitrogen.

    • Conclusions:

    • Freons represent a viable alternative cryogen for many dermatologic cryosurgery applications.
    • Freon 22 is identified as a practical choice for widespread clinical use.
    • Further research is required to fully understand the potential toxic effects of these fluorinated hydrocarbons.