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Related Experiment Videos

Iatrogenic multiple pregnancy.

Isaac Blickstein1, Louis G Keith

  • 1Department Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel. blick@netvision.net.il

Seminars in Neonatology : SN
|September 18, 2002
PubMed
Summary
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Maternal characteristics of preterm singleton birth following assisted reproduction: a population-based study.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2019

Physician-made multiple pregnancies (IMPs) drive twin and high-order multiple births, increasing risks of prematurity and low birth weight. Controlling embryo transfers can reduce adverse outcomes and costs associated with IMPs.

Area of Science:

  • Reproductive Medicine
  • Perinatology
  • Public Health

Background:

  • Iatrogenic - physician-made - multiple pregnancies (IMPs) are a significant factor in the rising rates of twin and high-order multiple births globally.
  • The primary cause of IMPs is the treatment of reduced fecundity, influenced by lifestyle changes in the latter half of the 20th century.
  • IMPs are linked to increased perinatal morbidity and mortality due to prematurity and low birth weights.

Purpose of the Study:

  • To analyze the contribution of iatrogenic - physician-made - multiple pregnancies to adverse perinatal outcomes.
  • To evaluate the impact of assisted conception techniques on monozygotic twinning and associated pathologies.
  • To propose strategies for reducing IMPs, adverse perinatal outcomes, and associated healthcare costs.

Main Methods:

Related Experiment Videos

  • Review of literature on iatrogenic - physician-made - multiple pregnancies and assisted conception.
  • Analysis of the relationship between fertility treatments, multiple births, and perinatal complications.
  • Evaluation of current practices in assisted reproduction concerning embryo transfer numbers.

Main Results:

  • Assisted conception techniques increase the incidence of monozygotic twinning and related complications.
  • Current management of IMPs involves a trade-off between maximizing success rates and minimizing adverse outcomes.
  • Significant reduction in adverse perinatal outcomes and costs is achievable through specific interventions.

Conclusions:

  • Eliminating procedures linked to unavoidable IMPs is crucial.
  • Controlling the number of embryos transferred during assisted conception can significantly lower rates of IMPs.
  • Implementing these changes can lead to improved perinatal health and reduced healthcare expenditures.